Biomedical Engineer, Neurophysiologist: Qiping Yu, PhD

yuDr. Qiping Yu, Associate Research Scientist at the Columbia University Medical Center, has been working in the Clinical Motor Physiology Laboratory since 1996. He has a joint PhD degree in Biomedical Engineering (Rutgers University) and Physiology (UMDNJ-RWJ Medical School). He did postdoctoral training in neurophysiology under Dr. Morton Cohen at the Albert Einstein College of Medicine. He is skilled in neurophysiological data processing, system analysis and modeling, intra- and extra-cellular neuronal recordings, and biomedical instrumentation. He has contributed to the development of our novel spiral analysis, EEG-EMG backaveraging, tremor and EMG profile analyses, and our microelectrode recording (MER) system used in deep brain stimulation (DBS) surgeries. He plays a critical role in the Center for Movement Disorder Surgery performing intra-operative MER-guided neurophysiologic on-line analysis, mapping and monitoring. Dr. Yu is an expert in neurophysiological tests and analysis-based differential diagnoses of patients with Parkinson’s disease (PD), myoclonus, dystonia and other conditions. His research includes quantitative methods of detecting kinematic and physiologic features of PD, tremors, and dystonia, and the effect of DBS on fine motor control in patients with PD. He is also investigating the utility of wavelet, bispectrum, and bicoherence analyses in the evaluation of movement disorders.

Recent publications:

Yu Q, Floyd AG, Goodman RR, McKhann GM, Winfield LM, Ford B and Pullman SL. Quantitative analysis of bilateral subthalamic nucleus stimulation on handwritten spirals in patients with Parkinson’s disease. Washington, DC: Society for Neuroscience 2006 (Submitted).

Louis ED, Yu Q, Floyd AG, Moskowitz C, Pullman SL. Axis is a feature of handwritten spirals in essential tremor. Movement Disorders 2006; e-pub available May 2006, In press.

Goodman RR, Kim B, McClelland S III, Senatus PB, Winfield LM, Pullman SL, Yu Q, Ford B, McKhann GM II. Operative techniques and morbidity with subthalamic nucleus deep brain stimulation in 100 consecutive patients with advanced Parkinson disease. Journal of Neurology, Neurosurgery and Psychiatry 2006; 77(1): 12-17.

Yu Q, Hristova AH, Floyd A and Pullman SL. Characteristics of surface EMG signals in patients with primary writing tremor and essential tremor using quantitative wavelet analysis. Washington, DC: Society for Neuroscience 2005.

Piboolnurak P, Yu QP, Pullman SL. Clinical and neurophysiologic spectrum of orthostatic tremor. Mov Disord 2005; 20(11): 1455-1461.

Piboolnurak P, Rothey N, Ahmed A, Ford B, Yu QP, Xu D, Pullman SL. Psychogenic tremor disorders identified using tree-based statistical algorithms and quantitative tremor analysis. Mov Disord 2005; 20(12): 1543-1549.

Yu Q, Nagashima M, Floyd A, Pullman, SL. Speed characteristics of handwriting spirals in patients with Parkinson’s Disease. Washington, DC: Society for Neuroscience 2004.

Gordon PH, Yu Q, Qualls C, Winfield H, Dillon S, Greene PE, Fahn S, Breeze RE, Freed CR, Pullman SL. Reaction time and movement time after embryonic cell implantation in Parkinson disease. Arch Neurol 2004; 61: 858-861.

Selected Publications

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